When biodiversity preservation meets biotechnology: The challenge of developing synthetic microbiota for resilient sustainable crop production

Agriculture needs to develop novel strategies and practices meet the increasing global food demand, in an ecological economical sustainable framework. The plant-associated microbiota is gaining attention as part of these since it strongly contributes plant health, nutrition, resilience environmental perturbations. However, domestication has brought reduction abilities recruit a beneficial microbiota. It becoming clear that successful use requires multifaceted approach where microbiologist, geneticists, scientists, agronomists, computational biologists can ways solutions modify both plant's ability it, directed increase crop performances. Here, while briefly reviewing state-of-the-art research, we focus on need discover, understand associated with wild relatives crops neglected crops, which harbour biodiversity needed for developing efficient bioinoculant solutions. In particular, emphasize convergence situ preservation microbiome preservation, provides added value nature habitat conservation, living collections biodiversity. heuristic bioinoculants (viz., synthetic communities) proper models predict outcome their applications also discussed toward systems-biology-guided development.